(R)-Azepan-3-amine
- CAS No.124932-43-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity (R)-Azepan-3-amine (CAS 124932-43-0) serves as a critical chiral intermediate for Besifloxacin synthesis, available in bulk with full COA.
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Product Overview
(R)-Azepan-3-amine is a specialized chiral amine intermediate extensively utilized in the pharmaceutical industry for the synthesis of advanced fluoroquinolone antibiotics. As a key building block, this compound plays a pivotal role in the manufacturing process of Besifloxacin hydrochloride, ensuring the necessary stereochemical configuration required for biological activity. Our facility produces this intermediate under strict quality control standards, guaranteeing high enantiomeric purity and consistent batch-to-batch reliability for global pharmaceutical partners.
The chemical structure features a seven-membered azepane ring with an amine group at the third position in the R-configuration. This specific stereochemistry is crucial for the efficacy of the final active pharmaceutical ingredient (API). We understand the critical nature of chiral intermediates in drug development and supply chain stability, which is why our production processes are optimized for scalability and purity.
Key Specifications
Our manufacturing protocol ensures that every batch meets rigorous analytical standards. The physical and chemical properties are carefully monitored to maintain consistency. Below are the typical specifications and test results based on our factory standard analysis.
| Parameter | Specification | Typical Result |
|---|---|---|
| CAS Number | 124932-43-0 | Conforms |
| Molecular Formula | C6H14N2 | Conforms |
| Molecular Weight | 114.19 g/mol | Conforms |
| Appearance | Colorless to light yellow liquid | Light yellow liquid |
| Purity (Assay) | ≥98.0% | 99.06% |
| Moisture Content | ≤2.0% | 0.72% |
| Isomer Impurity | ≤1.0% | 0.43% |
| Density | 0.9±0.1 g/cm3 | Conforms |
| Boiling Point | 180.9±8.0 °C | Conforms |
Industrial Applications
The primary application of (R)-Azepan-3-amine is as a precursor in the synthesis of Besifloxacin, a third-generation fluoroquinolone antibiotic used in ophthalmic solutions. The high purity of this intermediate directly impacts the quality and safety profile of the final drug product. Our material is suitable for large-scale commercial manufacturing as well as process development stages.
- Essential chiral building block for fluoroquinolone antibiotics.
- Used in the production of ophthalmic antimicrobial agents.
- Supports generic drug manufacturing and new formulation development.
- Compatible with standard organic synthesis routes for API production.
Quality Assurance and Packaging
We adhere to international quality management systems to ensure product safety and integrity. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing all test results against specifications. Our packaging options are designed to protect the chemical stability of the amine during transit and storage.
Standard packing includes 25kg cardboard drums, though we can accommodate custom requirements based on customer logistics needs. For storage, the product should be kept in a cool, dry, and well-closed container, protected from moisture and strong light or heat sources to prevent degradation. Our global supply chain ensures timely delivery to support your manufacturing schedules.
