(S)-2,2-Dimethylcyclopropanecarboxylic Acid

Product Overview

(S)-2,2-Dimethylcyclopropanecarboxylic Acid is a specialized chiral building block extensively utilized in the pharmaceutical industry. As a key precursor, this compound plays an indispensable role in the stereoselective synthesis of Cilastatin, a renal dehydropeptidase inhibitor often co-administered with carbapenem antibiotics. Our manufacturing process ensures high enantiomeric excess, guaranteeing the structural integrity required for downstream drug synthesis. We adhere to strict quality control protocols to deliver material that meets the rigorous demands of modern medicinal chemistry.

Technical Specifications

Industrial Applications

The primary application of this chiral acid lies in the production of Cilastatin. The specific (S)-configuration is critical for the biological activity and metabolic stability of the final pharmaceutical product. Beyond Cilastatin, this cyclopropane derivative serves as a versatile intermediate in the synthesis of various agrochemicals and fine chemicals requiring a rigid chiral cyclopropane motif. Our facility supports scale-up from pilot batches to commercial tonnage, ensuring consistent supply chain reliability for global partners.

Quality Assurance and Storage

Quality is paramount in pharmaceutical intermediate manufacturing. Each batch undergoes comprehensive analysis using HPLC and GC-MS to verify purity and chiral integrity. We provide a detailed Certificate of Analysis (COA) with every shipment. To maintain stability, the product should be stored in a cool, dry, and well-ventilated area. Containers must remain tightly closed to prevent moisture absorption or contamination. We offer flexible packaging options, including 25kg drums, customized to meet specific logistical requirements and ensure safe global transport.