Tetrahydrozoline Hydrochloride
- CAS No.522-48-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity Tetrahydrozoline Hydrochloride (CAS 522-48-5) compliant with USP standards. Ideal for pharmaceutical formulations requiring precise vasoconstrictive activity.
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Product Overview
Tetrahydrozoline Hydrochloride is a high-quality pharmaceutical intermediate and active ingredient widely recognized for its efficacy in ophthalmic and nasal formulations. As a selective alpha-adrenergic receptor agonist, this compound plays a critical role in modern over-the-counter therapeutic solutions. Our manufacturing process ensures exceptional purity and consistency, meeting the rigorous demands of global pharmaceutical supply chains. We specialize in providing bulk quantities suitable for large-scale production of eye drops and nasal sprays.
This chemical entity is synthesized under strict Good Manufacturing Practice (GMP) conditions. Each batch undergoes comprehensive analytical testing to verify identity, potency, and safety profiles. The compound is supplied as a stable hydrochloride salt, which enhances solubility and bioavailability in aqueous formulations. Our facility maintains advanced quality control systems to guarantee that every shipment conforms to international pharmacopoeia standards.
Quality Specifications
We adhere to the United States Pharmacopeia (USP) standards for Tetrahydrozoline Hydrochloride. The following table outlines the key analytical parameters and test results typical of our production batches. Our commitment to quality ensures that the material is free from harmful impurities and residual solvents, making it safe for sensitive mucosal applications.
| Items of Analysis | Standard of Analysis | Test Results |
|---|---|---|
| Appearance | White to off-white powder | Conforms |
| Identification | IR spectrum, UV spectrum, Reaction of Chlorides | Conforms, Conforms, Positive |
| Heavy metals (USP) | NMT 0.005% | <0.005% |
| Loss on drying (USP) | NMT 1.0% | 0.2% |
| Residue on ignition | NMT 0.1% | <0.1% |
| Related substances sum (TLC/HPLC) | NMT 2.0% / NMT 1.0% | <2.0% / 0.8% |
| Assay (in dried substance) | 98.0-100.5% | 99.7% |
| Residual solvents | Compliant with ICH guidelines | Not detected |
| Conclusion | Conforms to USP 39 | |
Industrial Applications
The primary application of Tetrahydrozoline Hydrochloride is in the formulation of vasoconstrictive agents. It is extensively used in the production of ophthalmic solutions designed to relieve redness associated with minor eye irritations. Additionally, it serves as a key active ingredient in nasal decongestant sprays. Pharmaceutical manufacturers value this intermediate for its reliable performance and stability in various pH conditions.
Our technical team supports clients with formulation guidance to ensure optimal integration of this active ingredient into final products. We understand the regulatory landscape and provide necessary documentation, including Certificates of Analysis (COA) and stability data. This support helps streamline the registration process for downstream pharmaceutical products.
Storage and Handling
To maintain product integrity, Tetrahydrozoline Hydrochloride should be stored in a cool, dry environment. Refrigeration is recommended for long-term storage to prevent degradation. The material must be kept in tightly closed containers away from light and moisture. Proper handling procedures should be followed to ensure safety during manufacturing operations. We recommend consulting the Safety Data Sheet (SDS) for detailed handling instructions and precautionary measures.
Why Choose Our Supply
- Consistent high purity exceeding 99 percent assay.
- Full compliance with USP and international regulatory standards.
- Reliable global logistics and timely delivery schedules.
- Comprehensive technical support and documentation.
- Competitive bulk pricing for large-scale manufacturers.
Partner with us for a secure supply of Tetrahydrozoline Hydrochloride. Our dedication to quality and customer service makes us a preferred choice for pharmaceutical companies worldwide. Contact our sales team today to request a quote or sample for your evaluation.
