Intermediates

[4-(trans-4-Propylcyclohexyl)phenyl]boronic Acid

  • CAS No.146862-02-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity boronic acid derivative designed for advanced Suzuki coupling reactions in pharmaceutical and OLED synthesis.

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Product Technical Details

Product Overview

[4-(trans-4-Propylcyclohexyl)phenyl]boronic Acid is a specialized organoboron compound engineered for high-performance chemical synthesis. As a critical building block in modern organic chemistry, this substance serves as a key intermediate in the construction of complex molecular architectures. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal choice for research and industrial scale applications requiring precise stoichiometry and reliability.

The compound features a stable cyclohexyl structure linked to a phenyl boronic acid moiety, providing excellent reactivity in cross-coupling reactions. We prioritize purity standards to minimize side reactions, ensuring optimal yields for downstream processes. This material is extensively utilized in the development of advanced electronic materials and therapeutic agents.

Key Specifications

Quality control is paramount in the production of fine chemical intermediates. Our facility adheres to strict analytical protocols to verify every parameter listed below. The low water content is particularly crucial for maintaining stability during storage and preventing premature hydrolysis during sensitive reaction conditions.

ParameterSpecification
Chemical Name[4-(trans-4-Propylcyclohexyl)phenyl]boronic Acid
CAS Number146862-02-4
Molecular FormulaC15H23BO2
Molecular Weight246.15 g/mol
AppearanceWhite powder
Assay (Purity)≥98.0%
Water Content≤0.50%
Density1.03 g/cm3
Boiling Point394.9°C at 760 mmHg
Flash Point192.7°C

Industrial Applications

This boronic acid derivative is primarily employed in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in medicinal chemistry and material science. In the pharmaceutical sector, it facilitates the synthesis of biaryl structures found in various active pharmaceutical ingredients (APIs). The high purity level ensures that impurities do not interfere with catalytic cycles, reducing waste and improving overall process efficiency.

In the field of organic light-emitting diodes (OLEDs), this compound acts as a precursor for liquid crystal materials and emissive layers. The trans-configuration of the propylcyclohexyl group contributes to favorable mesogenic properties, enhancing the performance of display technologies. Researchers value this intermediate for its ability to introduce specific steric and electronic properties into final products, enabling the tuning of material characteristics for specific device requirements.

Storage and Handling

To maintain integrity, store this product in a cool, dry, and well-ventilated area. Keep containers tightly closed to prevent exposure to moisture and air, which can degrade boronic acid functionalities over time. The material is classified under transport hazard class 3, requiring standard precautions for flammable solids during shipping. We offer flexible packaging options, including 25kg drums, customized to meet logistical needs. Comprehensive Certificates of Analysis (COA) are provided with every shipment to verify compliance with stated specifications.