(2R,3S)-3-Phenylisoserine Hydrochloride
- CAS No.132201-32-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity (2R,3S)-3-Phenylisoserine Hydrochloride serves as a critical chiral intermediate for Paclitaxel production. We offer bulk quantities with full quality documentation.
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Product Overview
(2R,3S)-3-Phenylisoserine Hydrochloride represents a critical chiral building block within the modern pharmaceutical landscape, specifically designed for complex organic synthesis workflows. This high-value intermediate is characterized by its specific stereochemistry, which is essential for ensuring the biological efficacy of downstream therapeutic agents. Our manufacturing process adheres to strict quality control protocols to guarantee consistency across batches, making it an ideal choice for large-scale pharmaceutical production and research development projects requiring precise molecular architecture.
Technical Specifications
We maintain rigorous standards for all chemical parameters to support reliable synthesis outcomes. The following table outlines the key physical and chemical properties verified through advanced analytical methods such as HPLC and NMR spectroscopy.
| Parameter | Value |
|---|---|
| CAS Number | 132201-32-2 |
| Molecular Formula | C9H12ClNO3 |
| Molecular Weight | 217.65 g/mol |
| Purity | ≥99.0% |
| Appearance | White powder |
| Melting Point | 222-224°C |
Industrial Applications
The primary application of this compound lies in the preparation of potent anticancer medications, most notably serving as a key intermediate in the synthesis of Paclitaxel. The specific (2R,3S) configuration is vital because the biological activity of the final drug product is highly dependent on the stereochemical purity of the starting materials. Utilizing high-grade intermediates reduces the risk of impurities that could complicate purification steps or affect the safety profile of the final pharmaceutical formulation. Beyond oncology, this amino acid derivative finds utility in various medicinal chemistry programs focused on developing novel therapeutic agents targeting cellular microtubule stability.
Quality Assurance and Control
Quality is the cornerstone of our supply chain commitment. Every batch undergoes comprehensive testing to verify identity, purity, and physical properties before release. Our quality assurance framework includes:
- Strict adherence to documented manufacturing processes and standard operating procedures.
- Complete traceability from raw material sourcing to final product packaging.
- Provision of detailed Certificates of Analysis (COA) with each shipment.
- Regular audits of production facilities to maintain compliance with industry standards.
- Stability testing to ensure product integrity during storage and transit.
Packaging and Storage Guidelines
To preserve the chemical stability and physical integrity of (2R,3S)-3-Phenylisoserine Hydrochloride, proper handling is essential. The product is typically packaged in 25 kg drums, though we accommodate custom packaging requirements based on specific client logistics and volume needs. Storage should be maintained in a cool, ventilated environment away from direct sunlight and moisture sources. Proper sealing of containers after use is recommended to prevent hygroscopic absorption, which could impact the purity levels required for sensitive synthetic reactions. Our logistics team ensures secure global shipping with appropriate documentation for customs clearance.
