N-(2,6-Dimethylphenyl)-2-piperazin-1-ylacetamide
- CAS No.5294-61-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate for Ranolazine synthesis. Off-white powder with ≥98.0% assay, ensuring reliable reaction yields and consistent quality for API production.
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Product Overview
N-(2,6-Dimethylphenyl)-2-piperazin-1-ylacetamide represents a sophisticated organic molecule primarily utilized within the pharmaceutical industry as a critical building block. This substance serves as a key intermediate in the multi-step synthesis of Ranolazine, a well-known therapeutic agent used in the management of chronic angina. Our manufacturing process ensures that each batch meets rigorous international standards, providing researchers and production facilities with a reliable source of high-quality chemical materials.
The molecular structure features a dimethylphenyl group linked to a piperazine ring via an acetamide bridge. This specific configuration is essential for the biological activity of the final active pharmaceutical ingredient. Maintaining high purity levels is paramount, as impurities can significantly affect downstream reaction yields and the safety profile of the final medication. We employ advanced purification techniques to guarantee consistency across all production lots, ensuring that our clients receive material that facilitates smooth scale-up processes.
Technical Specifications
Our quality control laboratory conducts comprehensive testing on every batch to verify physical and chemical properties. The following table outlines the standard specifications for this intermediate. Custom specifications may be available upon request for specific research and development projects requiring tailored parameters.
| Parameter | Value |
|---|---|
| CAS Number | 5294-61-1 |
| Molecular Formula | C14H21N3O |
| Molecular Weight | 247.336 g/mol |
| Appearance | Off-white powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 110-112 °C |
| Boiling Point | 411.2±45.0 °C |
| Density | 1.1±0.1 g/cm3 |
| Flash Point | 202.5±28.7 °C |
Industrial Applications
This compound is predominantly employed in the synthesis of cardiovascular medications. As a precursor to Ranolazine, it plays a vital role in the production pipeline for drugs aimed at improving blood flow to the heart muscle. Beyond standard API manufacturing, this intermediate is also valuable in medicinal chemistry research, where it serves as a reference standard or a starting material for analog development.
- Pharmaceutical API Synthesis: Essential step in producing anti-anginal medications.
- Process Development: Used for optimizing reaction conditions and scaling up manufacturing.
- Quality Control: Serves as a reference material for impurity profiling and method validation.
- Contract Manufacturing: Suitable for large-scale production under strict regulatory compliance.
Quality Assurance and Storage
We adhere to strict quality management systems to ensure product integrity. Each shipment is accompanied by a Certificate of Analysis (COA) detailing the test results obtained through HPLC and NMR spectroscopy. To maintain stability, the product should be stored in a cool, ventilated environment, away from direct sunlight and moisture. Proper storage ensures that the chemical properties remain unchanged over extended periods.
Packaging is designed to protect the material during transit. Standard packaging includes 25 kg drums, but we offer flexible solutions to meet specific customer logistics requirements. Our global supply chain capabilities ensure timely delivery to pharmaceutical manufacturers and research institutions worldwide. For technical inquiries or bulk pricing requests, our sales team is available to provide detailed support and documentation regarding safety data sheets and regulatory compliance.
