6-Hydroxy-2(1H)-3,4-dihydroquinolinone

Product Overview

6-Hydroxy-2(1H)-3,4-dihydroquinolinone is a high-value pharmaceutical intermediate characterized by its stable quinolinone structure. This compound serves as a critical building block in the synthesis of various therapeutic agents, most notably functioning as a key precursor in the manufacturing of Cilostazol. Our production facility adheres to rigorous international standards to ensure consistent molecular integrity and high purity levels suitable for downstream pharmaceutical applications.

The chemical structure features a hydroxy substitution at the sixth position of the dihydroquinolinone ring, providing specific reactivity profiles essential for multi-step organic synthesis. We specialize in scaling this molecule from laboratory research to industrial production, ensuring that supply chain continuity is maintained for our global partners in the medicinal chemistry sector.

Technical Specifications

Industrial Applications

The primary application of this intermediate lies within the cardiovascular pharmaceutical sector. It is extensively utilized as a starting material for the production of Cilostazol, a phosphodiesterase III inhibitor used to treat symptoms of intermittent claudication. The high purity of our supplied material ensures minimal impurity carry-over into the final active pharmaceutical ingredient (API), facilitating smoother regulatory filings and quality control processes for our clients.

Beyond its role in Cilostazol synthesis, this quinolinone derivative is explored in various research contexts involving heterocyclic chemistry. Its stability under standard storage conditions makes it a reliable choice for long-term project planning in drug discovery and development pipelines.

Quality Assurance and Packaging

Quality is paramount in our manufacturing process. Each batch undergoes comprehensive analysis using High-Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) spectroscopy to verify structural identity and purity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes.

Standard packaging consists of 25 kg drums lined with polyethylene bags to protect against moisture and contamination. Custom packaging solutions are available upon request to meet specific logistical requirements. We recommend storing the product in a cool, ventilated area away from direct sunlight and incompatible substances to maintain optimal stability over time.